Kluczowe i najlepiej przebadane zdolności peptydów kolagenowych mające wpływ na wygląd skóry to:
- stymulowanie proliferacji i ruchliwości fibroblastów (patrz Fakt nr 4);
- indukcja wzrostu gęstości i średnicy włókien kolagenowych w skórze właściwej;
- zwiększenie produkcji kwasu hialuronowego;
- ochrona skóry przed promieniowaniem UVA (patrz Fakt nr 11).
Na podstawie:
2 AN OVERVIEW OF THE BENEFICIAL EFFECTS OF HYDROLYSED COLLAGEN AS A NUTRACEUTICAL ON SKIN PROPERTIES SCIENTIFIC BACKGROUND AND CLINICAL STUDIES
SIBILLA, Sara, et al. An overview of the beneficial effects of hydrolysed collagen as a nutraceutical on skin properties: Scientific background and clinical studies. The Open Nutraceuticals Journal, 2015, 8.1.
10 TOPICAL APPLICATION AND ORAL SUPPLEMENTATION OF PEPTIDES IN THE IMPROVEMENT OF SKIN VISCOELASTICITY AND DENSITY
Maia Campos P.M., Melo M.O., Siqueira César F.C. Topical application and oral supplementation of peptides in the improvement of skin viscoelasticity and density. J. Cosmet. Dermatol. 2019
12 IMPROVEMENT OF SKIN CONDITION ON SKIN MOISTURE AND ANTI-MELANOGENESIS BY COLLAGEN PEPTIDES FROM MILKFISH (CHANOS CHANOS) SCALES
CHEN, Yu-Pei, et al. Improvement of skin condition on skin moisture and anti-melanogenesis by collagen peptides from milkfish (Chanos chanos) scales. In: IOP Conference Series: Materials Science and Engineering. IOP Publishing, 2018. p. 022067.
13 EFFECTS OF DIETARY SUPPLEMENTATION WITH FISH SCALES-DERIVE COLLAGEN PEPTIDES ON SKIN PARAMETERS AND CONDITION: A RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND STUDY
KOIZUMI, Seiko, et al. Effects of dietary supplementation with fish scales-derived collagen peptides on skin parameters and condition: A randomized, placebo-controlled, double-blind study. International Journal of Peptide Research and Therapeutics, 2018, 24: 397-402.
14 A COLLAGEN SUPPLEMENT IMPROVES SKIN HYDRATION, ELASTICITY, ROUGHNESS, AND DENSITY: RESULTS OF A RANDOMIZED, PLACEBO-CONTROLLED, BLIND STUDY
Bolke L, Schlippe G, Gerß J, Voss W. A Collagen Supplement Improves Skin Hydration, Elasticity, Roughness, and Density: Results of a Randomized, Placebo-Controlled, Blind Study. Nutrients. 2019 Oct 17;11(10):2494. doi: 10.3390/nu11102494. PMID: 31627309; PMCID: PMC6835901.
39 EFFECT OF DIFFERENT CONCENTRATIONS OF COLLAGEN, CERAMIDES, N-ACETYL GLUCOSAMINE, OR THEIR MIXTURE ON ENHANCING THE PROLIFERATION OF KERATINOCYTES, FIBROBLASTS AND THE SECRETION OF COLLAGEN AND/OR THE EXPRESSION OF mRNA OF TYPE I COLLAGEN
CHEN, R.-H., et al. Effect of different concentrations of collagen, ceramides, N-acetyl glucosamine, or their mixture on enhancing the proliferation of keratinocytes, fibroblasts and the secretion of colagen and/or the expression of mRNA of type I collagen. Journal of Food and Drug Analysis, 2008, 16.1: 11.
41 CHEMOTACTIC ATTRACTION OF HUMAN FIBROBLASTS TO TYPE I, II, AND III COLLAGENS AND COLLAGEN-DERIVED PEPTIDES
Postlethwaite AE, Seyer JM, Kang AH. Chemotactic attraction of human fibroblasts to type I, II, and III collagens and collagen-derived peptides. Proc Natl Acad Sci U S A. 1978 Feb;75(2):871-5. doi: 10.1073/pnas.75.2.871. PMID: 204938; PMCID: PMC411359.
42 EFFECTS OF INGESTION OF COLLAGEN PEPTIDE ON COLLAGEN FIBRILS AND GLYCOSAMINOGLYCANS IN THE DERMIS
Matsuda N, Koyama Y, Hosaka Y, Ueda H, Watanabe T, Araya T, Irie S, Takehana K. Effects of ingestion of collagen peptide on collagen fibrils and glycosaminoglycans in the dermis. J Nutr Sci Vitaminol (Tokyo). 2006 Jun;52(3):211-5. doi: 10.3177/jnsv.52.211. PMID: 16967766.
